Glycosphingolipid expression in squamous cell carcinoma of the upper aerodigestive tract
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چکیده
منابع مشابه
Glycosphingolipid expression in squamous cell carcinoma of the upper aerodigestive tract.
UNLABELLED Glycosphingolipids are integral constituents of cellular membrane, arranged in rafts, and with neoplastic cell anti-social behavior, like uncontrolled cell growth, invasiveness, and metastatic potential. AIM However, there are few studies about glycosphingolipids (GSL) expression in squamous cell carcinoma (SCC). Since GSL are known to be tumor-associated markers we decided to perf...
متن کاملRole of podoplanin expression in squamous cell carcinoma of upper aerodigestive tract.
Podoplanin, a type-1 transmembrane glycoprotein, was originally named due to its expression in renal podocytes of rats. It was subsequently detected in a variety of normal human tissues, including lymphatic endothelium. Although podoplanin has been identified as the endogenous ligand of C-type lectin-like receptor 2 (CLEC-2) on platelets, its physiological functions and pathways remain largely ...
متن کاملProton MR spectroscopy of squamous cell carcinoma of the upper aerodigestive tract: in vitro characteristics.
PURPOSE To determine the ability of in vitro high-field-strength proton MR spectroscopy to differentiate squamous cell carcinoma of the upper aerodigestive tract from uninvolved muscle. METHODS Surgical specimens of squamous cell carcinoma arising from the upper aerodigestive tract (n = 18) and from muscle (n = 13) were examined in vitro using high-field (11 T) proton MR spectroscopy. The pea...
متن کاملSquamous cell carcinoma of the esophagus and multiple primary tumors of the upper aerodigestive tract.
Squamous cell carcinoma of the esophagus is frequently associated with other, synchronous or metachronous tumors, in the upper aerodigestive tract. All 264 patients with squamous cell carcinoma of the esophagus, treated in the Gastrointestinal Surgery, Esophagus section, of the "Hospital das Clínicas" (São Paulo University Medical School, Brazil), between 1979 and 1989 were analyzed retrospecti...
متن کاملMUC4 and ErbB2 expression in squamous cell carcinoma of the upper aerodigestive tract: correlation with clinical outcomes.
OBJECTIVES/HYPOTHESIS Expression of the membrane mucin MUC4 has been associated with a variety of malignancies, including squamous cell carcinoma of the upper aerodigestive tract. MUC4 modulates cell signaling pathways as an intramembrane ligand of ErbB2. The hypotheses of the study were that MUC4 expression would correlate with ErbB2 expression and that MUC4 expression would correlate with cli...
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ژورنال
عنوان ژورنال: Brazilian Journal of Otorhinolaryngology
سال: 2006
ISSN: 1808-8694
DOI: 10.1016/s1808-8694(15)30030-6